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What is microcirculation?

What is Microcirculation and how does it work?

capillaroscopy machine

What is Microcirculation?

Microcirculation is the circulation of the blood in the smallest blood vessels, present within organ tissues. The microcirculation is composed of terminal arterioles, capillaries, and venules. Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries into the venules into the veins.In addition to these blood vessels, the microcirculation also includes lymphatic capillaries and collecting ducts. The main functions of the microcirculation are the delivery of oxygen and nutrients and the removal of carbon dioxide (CO2). It also serves to regulate blood flow and tissue perfusion thereby affecting blood pressure and responses to inflammation which can include edema (swelling).

Most vessels of the microcirculation are lined by flattened cells of the endothelium and many of them are surrounded by contractile cells called pericytes. The endothelium provides a smooth surface for the flow of blood and regulates the movement of water and dissolved materials in the interstitial plasma between the blood and the tissues.The microcirculation contrasts with macrocirculation, which is the circulation of blood to and from the organs.

How microcirculation work?


The AVACEN 100, Class-IIa, OTC medical device has been awarded the European Union CE (Conformité Européenne) Mark and is approved by Health Canada for the temporary increase of microcirculation.

AVACEN 100 U.S. FDA-Clearance: A heat therapy system indicated for the temporary relief of minor muscle and joint pain and stiffness; the temporary relief of joint pain associated with arthritis; muscle spasms; minor strains and sprains; muscular relaxation; and the temporary increase of local circulation where applied.

The AVACEN-100 uses the AVACEN Treatment Method to temporarily increase microcirculation to aid in the relief of minor muscle and joint pain and stiffness and the temporary relief of joint pain associated with conditions such as arthritis and fibromyalgia.

Getting your exercise and increasing your heart rate on a regular basis are obviously very good for your body.

what is microcirculation of blood

what is microcirculation through a capillary bed

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what is microcirculation

One of the reasons increased circulation is so good for you has to do with a lesser talked about subject of naturally increased microcirculation.

While circulation refers to blood flow to and from vital organs, microcirculation refers to blood flow in the smallest blood vessels in the body – capillaries, arterioles, and other such blood vessels. These blood vessels are often embedded in the organs, including the skin, and interact directly with muscle tissue.

Poor microcirculation is one of the single biggest contributing factors to almost all health problems: Diabetes, hypertension, vascular disease, atherosclerosis, kidney disease, Alzheimer’s, early aging and others. It is estimated that 80% of the population over the age of 40 may have moderately to extremely serious microcirculation problems and almost every non-injury related pain can be traced to a compromised microcirculation issue.

Until recently, there has never really been an increase in a body’s microcirculation without a proportionally larger increase in the body’s circulation. Meaning, you couldn’t really get the benefits of increased microcirculation without exercising, doing yoga, working out, going in a sauna or jacuzzi, stretching, water aerobics, or other activities that might get the blood flowing.

But continue reading and you will quickly see why increased microcirculation just may be exactly what your body needs to reduce pain and swelling on a daily basis.

Capillary Microcirculation

The main functions of the microcirculation are the delivery of oxygen and nutrients and the removal of carbon dioxide (CO2). It also serves to regulate blood flow and tissue perfusion thereby affecting blood pressure and responses to inflammation which can include edema (swelling).

The blood capillaries are where the important functions of the microcirculation take place: the exchange of material between circulation and cells. Capillaries are the smallest of the body’s blood vessels. They are only one cell thick, and they are the sites of the transfer of oxygen and other nutrients from the bloodstream to other tissues in the body; they also collect carbon dioxide waste materials and fluids for return to the veins.

Microcirculation Capillary Observation

Introduction: The AVACEN 100 continues to warm the blood passing through the treatment palm, which then circulates throughout the entire body increasing core body temperature. When core body temperature rises, pre-capillary arterioles dilate causing normally collapsed capillaries to open further improving microcirculation throughout the body. This allows excess heat to be dissipated by convection and radiation into the cooler ambient environment until the blood becomes cooler.

microcirculation microcirculation

Hypothesis: If the AVACEN 100 is effecting the entire body, then distant capillaries from the AVACEN treatment hand should exhibit increased blood flow (microcirculation) after treatment.

Materials and Methods: A microcirculation microscope (Shenzhen GH Biotechnology Development Co. model 380, with Cargille immersion oil type A), was used to observe capillary blood flow on the right hand ring finger in an area just below the finger nail (“Before” figure). The left hand was then treated using the AVACEN 100 medical device to infuse heat into the circulatory system for 20 minutes. Immediately following the AVACEN 100 treatment of the left hand, the same capillary area on the right hand was observed (“After” figure). To make sure the same capillaries were observed pre and post treatment, the finger was inserted into the stationary finger holder up to the point where a stop secured to the bottom side of the finger preventing further forward movement. All focusing and platform adjusters remained in the identical setting.

Results: A significant increase in capillary blood flow in the right hand immediately after AVACEN 100 treatment of the left hand palm was observed.

Fingernail Growth and Microcirculation

Fingernails reach their peak growth in the second and third decades, with a slight decline thereafter. A possible reason, is decreased blood flow and medical conditions that can affect it — like Raynaud’s phenomenon, which causes a spasmodic constriction of blood flow.

As the nail receives nutrition from blood flow, new nail plate cells are made. They push older nail plate cells forward extending the length of the nail. In humans, nails grow at an average rate of 3 mm (0.12 in) a month.

Using the AVACEN 100 has been shown to increase projected fingernail growth by approximately 400% of normal expected growth on both the treatment hand and the opposite hand. This is attributed to the increased microvascular circulation and nutrition initiated by the device.*

A 56 year old female was used in the pictures below. Only the left hand was used in the AVACEN 100 for a 6 day period. Using recognized nail growth calculations; the average age adjusted nail growth should be approximately 1/10th of an inch for an entire month . The pictures below shows the nail growth on the right hand to be approximately 1/10th of an inch in only 6 days.



The importance of microcirculation

A better supply of blood and therefore oxygen and nutrients to a cell means:

The cell functions better;

The organ works better;

All organs work better;

The whole organism works better;

Result: A person feels and is healthier!



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