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Nailfold capillaroscopy microscopy

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tasly microcirculation test

What is tasly microcirculation test application?

What is tasly microcirculation test application?

tasly microcirculation test Widefield capillary microscopy A technique used to evaluate finger nailfold capillaries, using a wide-angle stereomicroscope or ophthalmoscope; enlargement, ↑ tortuosity, or ↓ number of capillaries occur in connective tissue diseases–eg, Raynaud’s phenomenon, scleroderma–to evaluate extent of visceral involvement, MCTD, dermatomyositis, SLE.

Abstract. Nailfold capillaroscopy is a method of great diagnostic value in the differential diagnosis of primary versus secondary Raynaud´s phenomenon, of systemic sclerosis versus other so called connective tissue diseases and of additional diagnostic value in other entities. Rheumatologists, dermatologists, and angiologists in Germany have convened in an interdisciplinary working group in which they synergistically combined their expertise to develop a common nomenclature and standards for the technical performance of tasly microcirculation test. The article gives an overview of historical and technical aspects of capillaroscopy, morphologic findings, and disease-specific patterns. It also provides a critical appraisal of its significance in the diagnosis and sequelae of these interdisciplinarily-managed diseases including its performance in children and gives an excursion in the potential perspectives of capillaroscopy in less common indications.

tasly microcirculation test

What can analysis tasly microcirculation test?

What can analysis tasly microcirculation test?

(1) Hypertension: Enter sticks spasm, slender, showing hook-shaped pipe loop. Reduce the number of blood vessels, blood flow velocity faster.

(2) coronary artery disease: to reduce the number of loop tube, severe deformity, lower output and papillary venous plexus branch expansion, stasis. Erythrocyte aggregation, slow blood flow, blood plasma separation, severe blood was sand-like.

(3) hypotension: pipe loop hidden, more gentle, stiffness, redness of the skin lighter, slow blood flow or stagnation.

(4) chronic bronchitis, asthma, pulmonary heart disease: reducing the number of pipe loops, loop short loop or only see the top or disappear, pipe loop deformity, nipple vein dilation, blood flow is slow. Senile chronic bronchitis, which pipe loop than normal, but between milk under severe venous plexus dilatation.

(5) Diabetes: pipe loop fuzzy, deformity, the wall is not smooth, common flocculent pipe loop, blood viscosity is high, the flow rate is slow, sometimes dotted line shape.

(6) Liver: pipe loop deformity, not smooth, oozing or bleeding, severe red blood cell aggregation, blood flow is slow, severe venous plexus obvious.

(7) peripheral vascular disease (vasculitis): reduce the number of pipe loops, deformity, loop top bleeding, oozing or bleeding, blood flow is slow uneven.

(8) Rheumatology: pipe loop length extension spasms disappeared, pulse movement dilated, blood, red blood cell aggregation, thrombosis obvious, slow flow.

(9) Kidney Disease: pale background, loop week exudation, bleeding, blood stasis classes, reducing the number of pipe loops is not clear, uneven thickness, pipe loop tortuous twisting, spasms end arterioles, venules end opposite the relaxation, flow It slowed down.

(10) atherosclerosis: pipe loop deformation, distortion, wall coarse “twist” and “cross” shape more and bigger blood viscosity, slow blood flow level.

tasly microcirculation test

tasly microcirculation test: A Basic Screening Tool in Raynaud’s Phenomenon

tasly microcirculation test: A Basic Screening Tool in Raynaud’s Phenomenon

The term “Raynaud’s phenomenon” refers to a defined triphasic colour change pattern (white, blue, red) of the skin of the fingers. The initial pallor, which may lead to cyanosis (blue coloration) of the digits, is followed by reactive hyperemia and can be accompanied by numbness, paresthesias and pain. Raynaud’s is triggered by exposure to cold, emotional stress and specific drugs. Pathophysiologically it is characterized by an excessive vasoconstrictive response (dominance of vasoconstrisctive over vasodilatory factors) of the small arterioles and the digital arteries.Etiologically it can be classified as primary or secondary, mainly either to systemic sclerosis and related diseases, or to the thoracic outlet syndrome. As such, Raynaud’s phenomenon represents an important clinical manifestation of microvascular involvement. Rare cases of paraneoplastic Raynaud’s have been described, the pathogenesis of which remains unclarified, has however been most likely attributed to neuroendocrine substances secreted by the tumor.Despite the evolution of the technology involved over the decades, nailfold capillaroscopy remains very simple in principle. The term refers to the non-invasive observation of the nailfold capillary bed. Nailfold capillaroscopy can be performed with basic equipment such as a magnifying lens, an ophthalmoscope, a dermatoscope/ stereomicroscope or a conventional wide field microscope; the nailfold video capillaroscope, however, is the gold standard tool, and provides the technology for the visualization and analysis both of morphological as well as rheological parameters of the skin microvasculature. Qualitative and quantitative microangiopathic parameters that can be recorded and analyzed include, among others, microhemorrhages, plexus morphology, capillary density, and morphologic anomalies of the end row loops. In normal conditions, or in primary Raynaud’s, the normal nailfold capillaroscopic pattern shows a regular disposition of the capillary loops along with the nailbed. In subjects suffering from secondary Raynaud’s phenomenon, alterations of the capillaroscopic findings should alert the physician of the possibility of a connective tissue disease or other conditions not yet detected.This review aims to outline the major characteristics of the normal nailfold microvascular network and the healthy variations that may be encountered in relation to age, race, employment etc, and highlight its applicability not only as a powerful tool in the screening of a variety of vascular disorders, in particular of autoimmune origin, but also as a potent tool in the follow-up of patients with established microvascular disorders in response to treatment.As microcirculation involvement is attracting increasing interest in chronic vascular diseases such as diabetes mellitus or hypertension, as a prognostic marker for macrovascular disease and target organ involvement, the acquaintance with and application of techniques assessing microvascular compromise gains particular significance. The advantages of capillaroscopy (low cost, uninvasiveness, repeatability, high sensitivity, good specificity and easy interpretation of the results) render this technique a valuable asset for the clinician.

tasly microcirculation test

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