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Nailfold capillaroscopy microscopy

5 Questions to Ask Before You tasly microcirculation test

tasly microcirculation test

What is tasly microcirculation test Structure?

What is tasly microcirculation test Structure?

1. 8 inch monitor

2. imported chip CCD

3. fine handwheel

4. coarse handwheel

5. platform lateral movement

6. longitudinal movement of the platform

7. finger hold

8. image spot adjustment ( could totate from left and right )

tasly microcirculation test

What is tasly microcirculation test Testing conditions?

What is tasly microcirculation test Testing conditions?

1) Check the room temperature and humidity. Room temperature and humidity should be kept relatively constant. room temperature should be maintained in the 22-24 degree , relative humidity about 70%
2) The patient generally take seats, keep the height of the hand the same with heart
3) Preparation of paraffin oil or cedar oil.Drop 2 drops in the nailfold skin. (Purpose prove light transmission, and reduce skin scattering)
4) Testing generally be in the morning or afternoon, and review should at the same time every day .
5) The patient should
a. Avoiding intense activity or manual labor within one hour before testing
b. Take a rest about 15-30 minutes before testing
c. Can not take any drug which will affect the cardiovascular vessels before testing
d. Does not smoke , wash hands or eat within an hour before testing
e. Pay attention to the influence of the Female menstrual

tasly microcirculation test

What need the sensitiv imago?

What need the sensitiv imago?

The tasly microcirculation test in EU offers various groups of devices targeted at different categories of customers:

Doctors: for private practice, scientific purpouse
Holistic Centers: as the main health scan and diagnosis equipment
Nutritionists: alternative and preventive practice
Food supplements companies/distributors(Coral Club, NSP, Tiens, Dr.Nona and others): to exclude mistakes and accurately match their products with clients needs and expand their clientele
Manufacturers of cosmetics, foodstuffs and various kinds of remedies: for identifying of optimal ingredients and for evaluation tests of their products
Beauty salons and health centers: for adding a new high-price, in-demand service to their business
Individual entrepreneurs and investment companies: to open a recession-proof, turn-key business that can start generating you profits right away. We offer assistance to our customers in setting up their private diagnostic cente

tasly microcirculation test

Clinical significance of tasly microcirculation test in systemic lupus erythematosus

Clinical significance of tasly microcirculation test in systemic lupus erythematosus: correlation with endothelial cell activation markers and disease activity

Objective: To evaluate whether tasly microcirculation test (NC) changes are associated with the main serum endothelial cell activation markers and the disease activity of systemic lupus erythematosus (SLE).

Methods: Serum levels of vascular endothelial growth factor (VEGF), endothelin‐1 (ET‐1), soluble E‐selectin (sE‐selectin), and soluble thrombomodulin (sTM) were determined by an enzyme‐linked immunosorbent assay (ELISA) in 80 SLE patients and 33 healthy controls.

Results: Nailfold capillary abnormalities were seen in 74 out of 80 (92.5%) SLE patients. A normal capillaroscopic pattern or mild changes were found in 33 (41.25%) and moderate/severe abnormalities in 47 (58.75%) of all SLE patients. In SLE patients a capillaroscopic score >1 was more frequently associated with the presence of internal organ involvement (p<0.001) as well as with immunosuppressive therapy (p<0.01). Significant differences were found in VEGF (p<0.001), ET‐1 (p<0.001), sE‐selectin (p<0.01), and sTM (p<0.001) serum concentrations between SLE patients with a capillaroscopic score >1 and controls. SLE patients with severe/moderate capillaroscopic abnormalities showed significantly higher VEGF serum levels than patients with mild changes (p<0.001). Moreover, there was a significant positive correlation between the severity of capillaroscopic changes and the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) (p<0.005) as well as between capillaroscopic score and VEGF serum levels (p<0.001). Conclusions: Our findings confirm the usefulness of NC as a non‐invasive technique for the evaluation of microvascular involvement in SLE patients. A relationship between changes in NC, endothelial cell activation markers and clinical features of SLE suggest an important role for microvascular abnormalities in clinical manifestation of the disease.

tasly microcirculation test

tasly microcirculation test for Diagnosis of Secondary Raynaud

tasly microcirculation test for Diagnosis of Secondary Raynaud

Nailfold capillaroscopy can determine whether or not Raynaud’s is secondary to an illness such as scleroderma. Raynaud’s is often the first symptom of scleroderma, and may precede the onset of Scleroderma and other scleroderma symptoms by years or by months.

Only 5% to 20% of people with Raynaud’s phenomenon subsequently develop scleroderma, but about 90% of scleroderma patients experience this extreme cold sensitivity with red/blue flashes in their hands and feet as a primary manifestation of their disease. What Causes Raynaud’s? National Heart Lung and Blood Institute. NIH.
Low Risk for Developing Systemic Sclerosis

Some people with positive ANA and Raynaud’s never go on to develop a defined connective tissue disease (CTD).

A 2006 study presented at the American College of Rheumatology meeting showed that there is a subset of patients with positive ANA and Raynaud’s who never go on to develop systemic scleroderma.
High Risk Factors for Systemic Sclerosis

Raynaud’s + SSc Antibodies + Abnormal Nailfold = 60x Higher Risk of Systemic Sclerosis

Difficulties in diagnosis of systemic sclerosis-related interstitial lung disease (SSc-ILD). The diagnosis of SSc-ILD could maybe be made sooner if a capillaroscopy was performed earlier, according to the current criteria of early SSc. PMC, Respirol Case Rep, 2015 Sep; 3(3): 99–101.
tasly microcirculation test and Other Diseases

tasly microcirculation test and Other Diseases. Capillaroscopy can also be useful for the diagnosis of secondary Raynaud’s due to diseases other than scleroderma, including glaucoma, graft vs. host disease, rheumatoid arthritis, and vascular diseases.
Research on Nailfold Patterns in Systemic Sclerosis

Nailfold capillary abnormalities in erectile dysfunction (ED) of systemic sclerosis (SSc). Neither the presence or absence of abnormal capillaroscopy findings nor the subdivision into early, active and late patterns is associated with coexistent ED in SSc. PubMed,Rheumatology. (Also see Erectile Dysfunction and Scleroderma)

Nailfold capillaroscopy (NFC) abnormalities as predictors of mortality in patients with systemic sclerosis (SSc). Avascular scores higher than 1.5 at NFC was an independent predictor of death in SSc, suggesting that NFC can be useful for predicting SSc outcome. PubMed, Clin Exp Rheumatol.

tasly microcirculation test

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